Open Access

Acute myeloid leukemia post‑cytotoxic therapy following chemotherapy for thymoma: A case report

  • Authors:
    • Masahiro Manabe
    • Yoko Tani
    • Naoyuki Inano
    • Yuuji Hagiwara
    • Nobuhiro Sogabe
    • Satoru Nanno
    • Ki-Rhang Koh
  • View Affiliations

  • Published online on: January 11, 2024     https://doi.org/10.3892/mi.2024.133
  • Article Number: 9
  • Copyright : © Manabe et al. This is an open access article distributed under the terms of Creative Commons Attribution License [CC BY 4.0].

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Abstract

The present study reports the case of a patient with acute myeloid leukemia post‑cytotoxic therapy (AML‑pCT) that developed following chemotherapy for thymoma. A 64‑year‑old female patient underwent surgical resection for a mediastinal tumor and was diagnosed with stage IVa thymoma. She received chemotherapy, including carboplatin/etoposide, carboplatin/paclitaxel and amrubicin monotherapy. At 56 months following surgery, she developed blastosis and was diagnosed with AML‑pCT. As demonstrated herein, although treatment for thymoma is associated with a markedly lower frequency of myeloid neoplasms post‑cytotoxic therapy (MN‑pCT) than treatment for other malignancies, such as breast carcinoma, it is important to be aware that MN‑pCT may occur as a late complication of thymoma treatment.
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January-February 2024
Volume 4 Issue 1

Print ISSN: 2754-3242
Online ISSN:2754-1304

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Spandidos Publications style
Manabe M, Tani Y, Inano N, Hagiwara Y, Sogabe N, Nanno S and Koh K: Acute myeloid leukemia post‑cytotoxic therapy following chemotherapy for thymoma: A case report. Med Int 4: 9, 2024
APA
Manabe, M., Tani, Y., Inano, N., Hagiwara, Y., Sogabe, N., Nanno, S., & Koh, K. (2024). Acute myeloid leukemia post‑cytotoxic therapy following chemotherapy for thymoma: A case report. Medicine International, 4, 9. https://doi.org/10.3892/mi.2024.133
MLA
Manabe, M., Tani, Y., Inano, N., Hagiwara, Y., Sogabe, N., Nanno, S., Koh, K."Acute myeloid leukemia post‑cytotoxic therapy following chemotherapy for thymoma: A case report". Medicine International 4.1 (2024): 9.
Chicago
Manabe, M., Tani, Y., Inano, N., Hagiwara, Y., Sogabe, N., Nanno, S., Koh, K."Acute myeloid leukemia post‑cytotoxic therapy following chemotherapy for thymoma: A case report". Medicine International 4, no. 1 (2024): 9. https://doi.org/10.3892/mi.2024.133